How Are These Genes Inherited?

Genes run in families. Everyone has two copies of each gene — including the two genes associated with hereditary breast and ovarian cancer. These genes are called BRCA1 and BRCA2.

If someone carries a mutation in one of these genes, there is a 1 in 2 (50 percent) chance that they will pass that mutation on to each child. So knowing your genetic status can be important for your children — as well as other family members.

This table shows the chance that a relative of someone with a mutation for hereditary breast and ovarian cancer has also inherited the gene change.

Relationship to person with mutation

Chance that they have the mutation

Chance that they DO NOT have the mutation

Identical twin 100% 0%
Child, Parent, Sibling 50% 50%
Grandparent, Uncle, Aunt, Niece, Nephew 25% 75%
First Cousin 12.5% 87.5%

It is important to realize that someone who does not inherit one of these gene changes cannot pass on the genetic risk. However, if someone is found to have one of these changes, other family members can learn more about their individual risk and may choose to have testing.

Learn more about testing with our pre-test questionnaire: Start Questionnaire
this page last updated: December 6, 2007